Past pandemics highlighted the problem. It took six months to set up a research program for the 2009-2011 H1N1 pandemic. It missed the first wave of the outbreak. Zika and Ebola took a year. When the Ebola research plan was ready, the outbreak was over. And a vaccine for COVID-19 is expected to take even longer to develop: 12-18 months. The rapid rise of pandemic cases requires a fast, nimble, and flexible response.
The U.S took a step in the right direction in 2013 when the CDC awarded Abt a contract to establish an infrastructure of research hospitals and institutions to enable flu research to begin three days after an outbreak. The research platform, which CDC may use for COVID-19, identifies and enrolls patients with possible pandemic influenza infection and collects clinical specimens and medical information in a standardized way. The real-time data informs public health officials about testing and treatment practices, clinical characteristics, and outcomes of hospitalized pandemic patients. These findings help inform the response and rapidly adjust how we make decisions in emergencies.
Other nations must follow suit. What’s needed are:
- Rigorous national research strategies.
- International donor funding for such programs for developing countries and training in epidemiology and laboratory and data management.
- International donor investments in projects that investigate vaccine effectiveness for vulnerable groups.
- South-south assistance in which countries with data management systems share them with countries unable to develop their own.
- A standing pool of funding, financed by international donors and national governments, to jump start pandemic research.
The private sector is not going to put money into such research efforts just in case a pandemic occurs. The return on investment is too uncertain. Government must do what the private sector can’t or won’t do. It is the role of government—not the private sector—to safeguard the public.
We must have research capacity available when we need it—and we will need it. If the number of COVID-19 cases and deaths is anything close to projections, this may be an agonizing lesson with huge costs. Maybe governments finally will learn it. In theory it didn’t have to be this way. Warnings from the experts abounded. But it’s human nature to ignore distant threats, which pandemics always seem to be. So human nature may have made this painful experience inevitable. We can only hope and pray that we won’t repeat it.
Learn more about Abt’s COVID-19 Insights.